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陈红英

姓名:陈红英
学科:预防兽医学
系别: 预防兽医系
电话/传真:
电子邮件:chhy927@163.com
通讯地址:郑州市郑东新区龙子湖高校园区15号 河南农业大学龙子湖校区第一实验楼动物医学院 450046

 

简介
      陈红英,女,博士,教授、硕士/博士研究生导师,1965年9月出生,四川仁寿人。
      长期从事动物微生物学、动物生物制品学及分子生物学与克隆技术的教学/科研工作,积累了一定经验,且擅长新型动物疫苗的研发。2015-2016在美国Cornell University访学1年。
      教学上作为一名专业/专业基础课老师,多次获得教学考核优秀;指导本科学生参加创新创业项目、“挑战杯”等各种竞赛。担任班主任的班级,考研率70%以上。曾获得河南农业大学“优秀教师”、 “教书育人”先进个人、就业创业工作先进工作者等。
      科研上主持国家重点研发计划课题、河南省科技攻关项目、河南省科技研发计划联合基金项目、河南省重大科技公关项目、河南省产学研项目和河南省基础与前沿科技项目等项目。以第一或通讯作者发表论文200余篇,其中SCI期刊论文50余篇。获中华人民共和国农业农村部神农中华农业科技奖二等奖1项、河南省科技进步奖二等奖4项和三等奖2项、河南省星火奖三等奖1项和河南省教委科技进步奖一等奖1项,获得国家授权发明专利8项。副主编或参编著作6部,并有126个GenBank收录基因序列号。
研究领域
动物分子病毒学与分子免疫学及动物生物制品的研发
教授课程
本科生《动物微生物学》、《生物制品学》、《兽医生物制品学》
学历及培训经历
2002年9月-2005年6月 华南农业大学预防兽医学博士研究生
1989年9月-1992年6月 四川农业大学预防兽医学硕士研究生
1984年9月-1989年7月 四川农业大学 本科
工作经历
1992年7月-至今   河南农业大学 助理研究员(1995),副研究员(2005),副教授(2008),教授(2012)
2009年3月-2011年8月  河南农业大学 博士后
2015年11月-2016年11月  美国康奈尔大学访问学者
学术社会兼职
中国畜牧兽医学会禽病分会 会员
中国免疫学会 会员
河南省畜牧兽医学会传染病学分会 理事
河南省科技特派员
承担科研项目情况
1.国家重点研发计划课题:雷波县肉牛高效养殖技术集成与示范(2022YFD1601606)主持
2. 河南省科技攻关项目:新型猪繁殖与呼吸综合征与猪伪狂犬病二联活疫苗的创制与开发(2221 0211 0375)主持
3. 河南省科技研发计划联合基金项目:基于单个B细胞抗体技术抗猪流行性腹泻病毒中和抗体SIgA的研发(222103810016)主持
4.河南省产学研项目:新型猪圆环病毒2型与猪伪狂犬病二联活苗的研制与开发(132107000002)主持
5.河南省产学研项目:猪细小病毒VP2和猪IL-18基因重组猪伪狂犬病毒二联活疫苗的研制与开发(152107000003)主持
代表论著(*通讯作者)
1. Chen Hong-Ying, Yang Ming-Fan, Cui Bao-An*, Cui Pei,  Sheng Min, Chen Guo, Wang Shu-Juan, Geng Jing-Wei. Construction and immunogenicity of a recombinant fowlpox vaccine coexpressing S1 glycoprotein of infectious bronchitis virus and chicken IL-18 [J]. Vaccine 2010, 28(51): 8112-8119. (SCI, IF: 3.572)
2. Chen Hong-Ying, Shang Yan-Hong, Cui Bao-An*, Zhang Hong-Ying, Wang Zi-Xin, Wang  Ya-Dan,  Chao An-Jun,  Duan Ting-Yun. Immune responses of chickens inoculated with a recombinant fowlpox vaccine coexpressing HA of H9N2 AIV and chicken IL-18 [J]. Antiviral Res 2011, 91(1): 50-56. (SCI, IF: 4.439)
3. Chen Hong-Ying, Zhao Li, Wei Zhan-Yong, Cui Bao-An*, Wang Zhen-Ya, Li Xin-Sheng, Xia Ping-An, Liu Jin-Peng. Enhancement of the immunogenicity of an infectious laryngotracheitis virus DNA vaccine by a bicistronic plasmid encoding glycoprotein B and interleukin-18 [J]. Antiviral Res 2010, 87(2): 235-241. (SCI, IF: 4.301)
4. Chen Hong-Ying, Cui Bao-An*, Xia Ping-An, Li Xin-Sheng, Hu Gong-Zheng, Yang Ming-Fan, Zhang Hong-Ying, Wang Xue-Bin,  Cao Su-Fang, Zhang Long-Xian, Kang Xiang-Tao, Tu Ke. Cloning, in vitro expression and bioactivity of duck interleukin-18 mature protein[J]. Vet Immunol Immunopathol 2008,123(3-4): 205-214.(SCI, IF: 2.176)
5. Zhang Liu-Hui,  Wang Tong-XuanFu Peng-Fei, Zhao You-Yi, Li Hong-Xuan Li, Wang Dong-Mei, Ma Shi-Jie, Chen Hong-Ying*, Zheng Lan-Lan*. First Molecular Detection and Genetic Analysis of a Novel Porcine Circovirus (Porcine Circovirus 4) in Dogs in the World [J]. Microbiol Spectr 2023, e0433322. (SCI, IF: 9.043)
6. Xu Peng-Li, Zhang Yu, Zhao Yu, Zheng Hui-Hua, Han Hao-Ying, Zhang Hong-Xin, Chen Hong-Ying*, Yang Ming-Fan*, Zheng Lan-Lan. Detection and phylogenetic analysis of porcine circovirus type 3 in central China [J]. Transbound Emerg Dis 2018, 65(5): 1163-1169.(SCI, IF: 3.554)
7. Tian Run-Bo, Zhao Yu, Cui Jian-Tao, Zheng Hui-Hua, Xu Tong,  Hou Cheng-Yao, Wang Zhen-Ya, Li Xin-Sheng, Zheng Lan-Lan*, Chen Hong-Ying*. Molecular detection and phylogenetic analysis of Porcine circovirus 4 in Henan and Shanxi Provinces of China [J]. Transbound Emerg Dis 2021, 68(2): 276-282.(SCI, IF: 5.005)
8. Hou Cheng-Yao, Zhang Liu-Hui, Zhang Yuan-Hang, Cui Jian-Tao, Zhao Li, Zheng Lan-Lan*, Chen Hong-Ying*. Phylogenetic analysis of porcine circovirus 4 in Henan Province of China: A retrospective study from 2011 to 2021 [J]. Transbound Emerg Dis 2022, 69(4):1890-1901. (SCI, IF: 4.521)
9. Xu Tong, Chen Xi-Meng, Fu  Yin, Ai Yi, Wang Dong-Mei,  Wei Zhan-Yong, Li Xin-Sheng, Zheng Lan-Lan*, Chen Hong-Ying*. Cross-species transmission of an emerging porcine circovirus (PCV4): First molecular detection and retrospective investigation in dairy cows [J]. Vet Microbiol 2022, 273: 109528 (SCI, IF: 3.246)
10. Wu huansheng, Hou ChengYao,  Wang Ziru, Meng Puyan, Chen Hong-Ying*, Cao Huabin*. First complete genomic sequence analysis of porcine circovirus type 4 (PCV4) in wild boars [J].Vet Microbiol 2022, 273: 109547(SCI, IF: 3.246)
11. Zhang Yuan-hang, Li Hong-xuan, Chen Xi-meng, Zhang Liu-hui, Zhao You-yi, Luo Ai-fang, Yang Yu-rong, Zheng Lan-lan*, Chen Hong-Ying*. Genetic Characteristics and Pathogenicity of a Novel Porcine Epidemic Diarrhea Virus with a Naturally Occurring Truncated ORF3 Gene [J]. Viruses 2022, 14(3): 487. (SCI, IF: 5.818)
12. Zheng Hui-Hua, Fu Peng-Fei, Chen Hong-Ying*, Wang Zhen-Ya*. Pseudorabies Virus: From Pathogenesis to Prevention Strategies [J]. Viruses 2022, 14(8): 1638.(SCI, IF: 5.818)
13. Chen Ximeng, Li Hongxuan, Zhu Qianlei, Chen HongYing*, Wang ZhenYa*, Zheng Lanlan, Liu Fang, Wei Zhanyong. Serological Investigation and Genetic Characteristics of Pseudorabies Virus between 2019 and 2021 in Henan Province of China [J]. Viruses 2022, 14(8): 1685.(SCI, IF: 5.818)
14. Zheng Hui-Hua, Bai Yi-Lin, Xu Tong, Zheng Lan-Lan, Li Xin-Sheng, Chen Hong-Ying*, Wang Zhen-Ya*. Isolation and Phylogenetic Analysis of Reemerging Pseudorabies Virus Within Pig Populations in Central China During 2012 to 2019 [J]. Front Vet Sci 2021, 8: 764982. (SCI, IF: 3.412)
15. Zheng Hui-Hua, Jin Yue, Hou Cheng-Yao, Li Xin-Sheng, Zhao Li, Wang Zhen-Ya*, Chen Hong-Ying*. Seroprevalence investigation and genetic analysis of pseudorabies virus within pig populations in Henan province of China during 2018-2019 [J]. Infect Genet Evol 2021, 92: 104835. (SCI, IF: 3.342)
16. Xu Tong, Zhang Yuan-Hang, Tian Run-Bo, Hou Cheng-Yao, Li Xin-Sheng, Zheng Lan-Lan, Wang Lin-Qing*, Chen Hong-Ying*. Prevalence and genetic analysis of porcine circovirus type 2 (PCV2) and type 3 (PCV3) between 2018 and 2020 in central China [J]. Infect Genet Evol 2021, 94: 105016. (SCI, IF: 3.342)
17. Xu Tong, Hou Cheng-Yao, Zhang Yuan-Hang, Li Hong-Xuan, Chen Xi-Meng, Pan Jia-Jia*, Chen Hong-Ying*. Simultaneous detection and genetic characterization of porcine circovirus 2 and 4 in Henan province of China [J]. Gene. 2022, 808: 145991. (SCI, IF: 3.688)
18. Hou Cheng-Yao, Xu Tong, Zhang Liu-Hui, Cui Jian-Tao, Zhang Yuan-Hang, Li Xin-Sheng, Zheng Lan-Lan*, Chen Hong-Ying*. Simultaneous detection and differentiation of porcine circovirus 3 and 4 using a SYBR Green І-based duplex quantitative PCR assay [J]. J Virol Methods 2021, 293:114152. (SCI, IF: 2.014)
19. Xu Peng-Li, Zhao Yu, Zheng Hui-Hua, Tian Run-Bo, Han Hao-Ying, Chen Hong-Ying*, Zheng Lan-Lan*. Analysis of genetic variation of porcine circovirus type 2 within pig populations in central China [J]. Arch Virol 2019,164(5): 1445-1451.(SCI, IF:2.243)
20. Cui Jian-Tao, Qiao Han, Hou Cheng-Yao, Zheng Hui-Hua, Li Xin-Sheng, Zheng Lan-Lan*, Chen Hong-Ying*. Characteristics of the spike and ORF3 genes of porcine epidemic diarrhea virus in Henan and Shanxi provinces of China [J]. Arch Virol 2020,26: 1-11(SCI, IF: 2.243)
21. Zhao Yu, Wang Lin-Qing,  Zheng Hui-Hua, Yang Yu-Rong,  Liu Fang, Zheng Lan-Lan, Jin Yue*, Chen Hong-Ying*.  Construction and immunogenicity of a gE/gI/TK-deleted PRV based on porcine pseudorabies virus variant [J]. Mol Cell Probes 2020, 53: 101605. (SCI, IF: 1.951).
22. Zheng Hui-Hua, Zhang Shu-Jian, Cui Jian-Tao, Zhang Jia,  Wang Le-yi, Liu Fang*, Chen Hong-Ying*. Simultaneous detection of classical swine fever virus and porcine circovirus 3 by SYBR green I-based duplex real-time fluorescence quantitative PCR [J]. Mol Cell Probes 2020, 50: 101524.(SCI, IF: 1.951)
23. Jia Yunfei, Zhu Qianlei, Xu Tong, Chen Ximeng, Li Hongxuan, Ma Mengyao, Zhang Yibei, He Zejun*, Chen Hongying*. Detection and genetic characteristics of porcine circovirus type 2 and 3 in Henan province of China [J].  Mol Cell Probes 2022, 61: 101790.(SCI, IF: 3.285)
24. Zhang Liu-hui, Wang Ling-qing, Li Hong-xuan, Zhang Hong-lei, Zheng Lan-lan, Chen Xi-meng*, Chen Hong-ying*. Detection and genetic analysis of porcine circovirus-like virus in pigs with diarrhea between 2016 and 2021 in Henan and Shanxi provinces of China [J]. Arch Virol 2023,168(2):76. (SCI, IF: 2.685)
成果奖励
1. 2012,鸡鸭IL-18基因的克隆、表达及免疫调节中应用研究,河南省人民政府,河南省科学技术进步奖,二等奖,2012-J-35-R01/10,第一名.
2. 2013,禽流感病毒突变株(H9亚型)HN106株多联疫苗的研制与开发,河南省人民政府,河南省科学技术进步奖,二等奖,2013-J-024-R02/10,第二名.
3. 2009,猪繁殖障碍性疾病PCR诊断方法建立及标准制定,河南省人民政府,河南省科学技术进步奖,二等奖,2009-J-036-R03/10,第三名.
4. 2019,猪主要病毒病防控关键技术创新与应用,河南省人民政府,河南省科学技术进步奖,三等奖,2019-J-151-R01/07,第已名.
5. 2019,家禽重要传染病基因工程疫苗创制与产业化,中华人民共和国农业农村部神农中华农业科技奖,二等奖,第四名.
6. 2015,表达猪圆环病毒2型ORF2基因的重组PRV毒株及其制备方法,授权国家发明专利,ZL201310242909.3,第一名.
7. 2019,一种猪伪狂犬病毒株,授权国家发明专利,ZL201510569963.8,第一名.
8. 2021,一种猪伪狂犬病双基因缺失变异突变病毒毒株及其构建方法,授权国家发明专利,ZL 2019 1 0651764.X,第一名.
9. 2015,一种猪细小病毒毒株,授权国家发明专利,ZL201310235390.6,第二名. 
荣誉称号
1.2012年获河南农业大学“优秀教师”;
2.2012年获河南农业大学“教书育人”先进个人
3.2019年河南农业大学优秀共产党员
寄语动医学子
珍惜大学四年时光,多读书,以便将来更好地服务于社会。