姓名：杨旭
学科：临床兽医学
系别：临床兽医系
电话/传真：
电子邮件：yangxu@henau.edu.cn
通讯地址：郑州市郑东新区龙子湖高校园区15号 河南农业大学龙子湖校区第一实验楼动物医学院 450046
简介
杨旭，男，博士，副教授，担任学院教学科研基地副主任。
教学上主讲兽医内科学本科课程。科研上聚焦霉菌毒素毒性机制的发掘。近年来主持各级项目7项，参与项目4项。指导国际级/校级大学生创新创业训练项目3项，指导本科生获中国小动物技能大赛二等奖，指导研究生获中华农业基金会“青年兽医拔尖人才”称号。
教授课程
本科生课程《兽医内科学》和《兽医学概论》
研究生课程《兽医临床实验检验技术》、《动物营养代谢病专题》和《兽医临床诊疗新技术》
研究领域
动物营养代谢与中毒病
学历及培训经历
2017年9月-2020年6月 东北农业大学 临床兽医学博士研究生
2014年9月-2017年6月 东北农业大学 临床兽医学硕士研究生
2010年9月-2014年6月 黑龙江八一农垦大学 动物医学本科
工作经历
2024年01月-至今 河南农业大学 副教授
2020年07月-2023年12月 河南农业大学讲师（校聘副教授）
学术社会兼职
1. 担任“科创中国”草食兽健康养殖专业科技服务团专家
2. 河南省农业农村厅农业科技服务体系专家
3. 中国畜牧兽医学会动物毒物学分会理事
4. 中国畜牧兽医学会兽医内科与诊疗学分会理事
5. 担任Animals、Toxics和life等期刊客座编辑
承担科研项目情况
1. 国家自然科学基金青年基金 2023.01至2025.12 主持
2. 河南省高等学校重点科研项目 2023.01至2024.12 主持
3. 中国博士后科学基金面上项目 2020.11至2022.06 主持
4. 河南省科技攻关项目 2021-01至2022-12 主持
5. 河南省博士后科研启动基金2020-07至2022-06 主持
6. 河南农业大学青年英才项目 2020.09-2025.09 主持
7. 河南农业大学科技创新基金 2021.01-2023.12 主持
代表论著（*通讯作者）
仅展示近五年论文：
1.Shanshan Zhang, Wenxi Song, Zeao Hua, Juanjuan Du, Ricardo Barbosa Lucena, Xuebing Wang, Cong Zhang, Xu Yang*, Overview of T-2 Toxin Enterotoxicity: From Toxic Mechanisms and Detoxification to Future Perspectives[J]. J Agric Food Chem. 2024, 72 (7): 3314-3324. IF: 6.1, 中科院一区TOP期刊.
2.Xu Yang, Pengli Liu, Yilong Cui, Miao Song, Xuliang Zhang, Cong Zhang, Yibao Jiang, Yanfei Li*, T-2 Toxin Caused Mice Testicular Inflammation Injury via ROS-Mediated NLRP3 Inflammasome Activation[J]. J Agric Food Chem. 2022; 70 (43): 14043-14051. IF: 6.1, 中科院一区TOP期刊.
3.Xu Yang, Pengli Liu, Yilong Cui, Bonan Xiao, Menglin Liu, Miao Song, Wanyue Huang, Yanfei Li*, Review of the reproductive toxicity of T-2 toxin[J]. J Agric Food Chem. 2020, 68 (3), 727-734. IF: 4.192, 中科院一区TOP期刊.
4.Jingjing Liu, Yingkui Gao, Huaqiang Zhang, Zhonghua Hao, Guangwei Zhou, Haojie Wen, Qing Su, Chao Tong*, Xu Yang*, Xuebing Wang*. Forsythiaside A attenuates Mastitis via PINK1/Parkin-mediated mitophagy[J]. Phytomedicine. 2024, 125: 155358. IF: 7.9, 中科院一区TOP期刊.
5.Wenxi Song, Youshuang Wang, Tingyu Huang, Yu Liu, Fengjuan Chen, Yunhe Chen, Yibao Jiang, Cong Zhang, Xu Yang*, T-2 toxin metabolism and its hepatotoxicity: New insights on the molecular mechanism and detoxification[J]. Environ Pollut. 2023, 1; 330: 121784. IF: 8.8, 中科院二区TOP期刊.
6.Fengjuan Chen, Youshuang Wang, Yunhe Chen, Jiayan Fan, Cong Zhang, Xiuyuan He, Xu Yang*, JNK molecule is a toxic target for IPEC-J2 cell barrier damage induced by T-2 toxin[J]. Ecotoxicol Environ Saf. 2023, 263:115247. IF: 6.8, 中科院二区TOP期刊.
7.Xu Yang, Wenxi Song, Kefei Zhang, Youshuang Wang, Fengjuan Chen, Yunhe Chen, Tingyu Huang, Yibao Jiang, Xuebing Wang, Cong Zhang*, p38 mediates T-2 toxin-induced Leydig cell testosterone synthesis disorder[J]. Ecotoxicol Environ Saf. 2023 15; 253: 114695. IF: 6.8, 中科院二区TOP期刊.
8.Xu Yang, Pengli Liu, Xuliang Zhang, Jian Zhang, Yilong Cui, Miao Song, Yanfei Li*, T-2 toxin causes dysfunction of Sertoli cells by inducing oxidative stress[J]. Ecotoxicol Environ Saf. 2021, 1:225:112702. IF: 7.129, 中科院二区TOP期刊.
9.Xu Yang, Yunhe Chen, Wenxi Song, Tingyu Huang, Youshuang Wang, Zhong Chen, Fengjuan Chen, Yu Liu, Xuebing Wang, Yibao Jiang, Cong Zhang*, Review of the Role of Ferroptosis in Testicular Function[J]. Nutrients. 2022;14(24):5268. IF:5.9, 中科院二区TOP期刊.
10.Ting-Yu Huang, Wen-Xi Song, You-Shuang Wang, Yu Liu, Feng-Juan Chen, Yun-He Chen, Yi-Bao Jiang, Cong Zhang, Xu Yang*, A review of anorexia induced by T-2 toxin[J]. Food Chem Toxicol. 2023; 179: 113982. IF: 4.3, 中科院三区.
11.Yang Xu, Huang Ting-Yu, Chen Yun-He, Chen Feng-Juan, Liu Yu, Wang You-Shuang, Song Wen-Xi, Zhang Jun-Tao, Jiang Yi-Bao, Wang Fang-Yu, Zhang Cong*. Deoxynivalenol induces testicular ferroptosis by regulating the Nrf2/System Xc-/GPX4 axis[J]. Food Chem Toxicol. 2023, 175:113730. IF: 4.3, 中科院三区.
12.Youshuang Wang, Yu Liu, Tingyu Huang, Yunhe Chen, Wenxi Song, Fengjuan Chen, Yibao Jiang, Cong Zhang, Xu Yang*, Nrf2: A Main Responsive Element of the Toxicity Effect Caused by Trichothecene (T-2) Mycotoxin[J]. Toxics. 2023;11(4):393. IF: 4.6, 中科院三区期刊.
13.Zhang Cong, Chen Feng-Juan, Wang You-Shuang, Zhang Ke-Fei, Yang Xu*, Wang Xue-Bing*. Tanshinone IIA protects intestinal epithelial cells from deoxynivalenol-induced pyroptosis[J]. Ecotoxicol Environ Saf. 2023, 28;269:115743. IF: 6.8, 中科院二区TOP期刊.
14.Cong Zhang, Youshuang Wang, Xinyu Zhang, Kefei Zhang, Fengjuan Chen, Jiayan Fan, Xuebing Wang, Xu Yang*. Maintaining the mitochondrial quality control system was a key event of tanshinone IIA against deoxynivalenol-induced intestinal toxicity[J]. Antioxidants (Basel). 2024, 18;13(1):121. IF: 7.0, 中科院二区.
1.Shanshan Zhang, Wenxi Song, Zeao Hua, Juanjuan Du, Ricardo Barbosa Lucena, Xuebing Wang, Cong Zhang, Xu Yang*, Overview of T-2 Toxin Enterotoxicity: From Toxic Mechanisms and Detoxification to Future Perspectives[J]. J Agric Food Chem. 2024, 72 (7): 3314-3324. IF: 6.1, 中科院一区TOP期刊.
2.Xu Yang, Pengli Liu, Yilong Cui, Miao Song, Xuliang Zhang, Cong Zhang, Yibao Jiang, Yanfei Li*, T-2 Toxin Caused Mice Testicular Inflammation Injury via ROS-Mediated NLRP3 Inflammasome Activation[J]. J Agric Food Chem. 2022; 70 (43): 14043-14051. IF: 6.1, 中科院一区TOP期刊.
3.Xu Yang, Pengli Liu, Yilong Cui, Bonan Xiao, Menglin Liu, Miao Song, Wanyue Huang, Yanfei Li*, Review of the reproductive toxicity of T-2 toxin[J]. J Agric Food Chem. 2020, 68 (3), 727-734. IF: 4.192, 中科院一区TOP期刊.
4.Jingjing Liu, Yingkui Gao, Huaqiang Zhang, Zhonghua Hao, Guangwei Zhou, Haojie Wen, Qing Su, Chao Tong*, Xu Yang*, Xuebing Wang*. Forsythiaside A attenuates Mastitis via PINK1/Parkin-mediated mitophagy[J]. Phytomedicine. 2024, 125: 155358. IF: 7.9, 中科院一区TOP期刊.
5.Wenxi Song, Youshuang Wang, Tingyu Huang, Yu Liu, Fengjuan Chen, Yunhe Chen, Yibao Jiang, Cong Zhang, Xu Yang*, T-2 toxin metabolism and its hepatotoxicity: New insights on the molecular mechanism and detoxification[J]. Environ Pollut. 2023, 1; 330: 121784. IF: 8.8, 中科院二区TOP期刊.
6.Fengjuan Chen, Youshuang Wang, Yunhe Chen, Jiayan Fan, Cong Zhang, Xiuyuan He, Xu Yang*, JNK molecule is a toxic target for IPEC-J2 cell barrier damage induced by T-2 toxin[J]. Ecotoxicol Environ Saf. 2023, 263:115247. IF: 6.8, 中科院二区TOP期刊.
7.Xu Yang, Wenxi Song, Kefei Zhang, Youshuang Wang, Fengjuan Chen, Yunhe Chen, Tingyu Huang, Yibao Jiang, Xuebing Wang, Cong Zhang*, p38 mediates T-2 toxin-induced Leydig cell testosterone synthesis disorder[J]. Ecotoxicol Environ Saf. 2023 15; 253: 114695. IF: 6.8, 中科院二区TOP期刊.
8.Xu Yang, Pengli Liu, Xuliang Zhang, Jian Zhang, Yilong Cui, Miao Song, Yanfei Li*, T-2 toxin causes dysfunction of Sertoli cells by inducing oxidative stress[J]. Ecotoxicol Environ Saf. 2021, 1:225:112702. IF: 7.129, 中科院二区TOP期刊.
9.Xu Yang, Yunhe Chen, Wenxi Song, Tingyu Huang, Youshuang Wang, Zhong Chen, Fengjuan Chen, Yu Liu, Xuebing Wang, Yibao Jiang, Cong Zhang*, Review of the Role of Ferroptosis in Testicular Function[J]. Nutrients. 2022;14(24):5268. IF:5.9, 中科院二区TOP期刊.
10.Ting-Yu Huang, Wen-Xi Song, You-Shuang Wang, Yu Liu, Feng-Juan Chen, Yun-He Chen, Yi-Bao Jiang, Cong Zhang, Xu Yang*, A review of anorexia induced by T-2 toxin[J]. Food Chem Toxicol. 2023; 179: 113982. IF: 4.3, 中科院三区.
11.Yang Xu, Huang Ting-Yu, Chen Yun-He, Chen Feng-Juan, Liu Yu, Wang You-Shuang, Song Wen-Xi, Zhang Jun-Tao, Jiang Yi-Bao, Wang Fang-Yu, Zhang Cong*. Deoxynivalenol induces testicular ferroptosis by regulating the Nrf2/System Xc-/GPX4 axis[J]. Food Chem Toxicol. 2023, 175:113730. IF: 4.3, 中科院三区.
12.Youshuang Wang, Yu Liu, Tingyu Huang, Yunhe Chen, Wenxi Song, Fengjuan Chen, Yibao Jiang, Cong Zhang, Xu Yang*, Nrf2: A Main Responsive Element of the Toxicity Effect Caused by Trichothecene (T-2) Mycotoxin[J]. Toxics. 2023;11(4):393. IF: 4.6, 中科院三区期刊.
13.Zhang Cong, Chen Feng-Juan, Wang You-Shuang, Zhang Ke-Fei, Yang Xu*, Wang Xue-Bing*. Tanshinone IIA protects intestinal epithelial cells from deoxynivalenol-induced pyroptosis[J]. Ecotoxicol Environ Saf. 2023, 28;269:115743. IF: 6.8, 中科院二区TOP期刊.
14.Cong Zhang, Youshuang Wang, Xinyu Zhang, Kefei Zhang, Fengjuan Chen, Jiayan Fan, Xuebing Wang, Xu Yang*. Maintaining the mitochondrial quality control system was a key event of tanshinone IIA against deoxynivalenol-induced intestinal toxicity[J]. Antioxidants (Basel). 2024, 18;13(1):121. IF: 7.0, 中科院二区.
成果奖励
1. 第二届全国博士后创新创业大赛-生猪智能养殖系统创建与应用，铜奖，第二完成人
2. 一种牲畜用腹部防寒马夹，实用新型专利，第二完成人
3. 牛群健康状况及经济效益管理系统V1.0，软件著作权，第一完成人
4. T-2 Toxin Caused Mice Testicular Inflammation Injury via ROS-Mediated NLRP3 Inflammasome Activation，河南省优秀科技论文一等奖，第一完成人
5. T-2 toxin causes dysfunction of Sertoli cells by inducing oxidative stress，河南省优秀科技论文二等奖，第一完成人
荣誉称号
1. 2021年度河南农业大学“优秀工会工作者”
2. 2022届河南农业大学本科毕业论文优秀指导教师奖
3. 2022年动物医学院“校庆先进个人”
4. 2023届河南农业大学本科毕业论文优秀指导教师奖
5. 2023年度河南农业大学“优秀工会工作者”
寄语动医学子
一分耕耘 一分收获
